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Patients admitted to the ICU with acute hypoxemic respiratory failure often receive supplemental oxygen with a high FIO2, which results in a high PaO2 and may be associated with increased mortality. Guidelines give no recommended oxygenation targets for adults in the ICU owing to sparse evidence. New research findings are summarized in a short video. https://nej.md/3s7pVqM | The New England Journal of Medicine
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