B-cell development from HSC (hematopoietic stem cell) to mature B cell takes 1 to 2 weeks and a carefully regulated sequence of events.

Overview of B Cell Development B cell development consists of several distinct stages of B cell development, each characterized by specific genetic changes and surface markers. This …

Jun 7, 2025 · The B lymphocyte is one of the most important cells of the body. This article will focus on the development of B cells and its main types.

Sep 1, 2008 · Finally, perturbations in B-cell development that give rise to certain types of congenital immunodeficiency, leukemia/lymphoma, and autoimmune disease are discussed in …

Early B cell development and commitment to the B cell lineage occurs in the foetal liver prenatally, before continuing in the bone marrow throughout life. B cells are at the centre of the adaptive …

Finally, perturbations in B-cell development that give rise to certain types of congenital immunodeficiency, leukemia/lymphoma, and autoimmune disease are discussed in the context …

Mar 6, 2025 · Explore B cell development, types, and functions in adaptive immunity, including antibody production and antigen presentation.

Throughout B cell development, the developing cells are interacting closely with the stromal cells of the bone marrow, which are largely composed of mesenchymal stem cells.