BMJ2d
Protection against murine osteoarthritis by inhibition of the 26S proteasome and lysine-48 linked ubiquitination
Objectives To determine whether the process of ubiquitination and/or activity of the 26S proteasome are involved in the induction of osteoarthritis (OA). Methods Bovine cartilage resorption assays, ...
BMJ5d
2016 American College of Rheumatology/European League Against Rheumatism classification criteria for primary Sjögren's syndrome
Objectives To develop and validate an international set of classification criteria for primary Sjögren's syndrome (SS) using guidelines from the American College of Rheumatology (ACR) and the European ...
BMJ6d
Impact of treatment with biologic DMARDs on the risk of sepsis or mortality after serious infection in patients with rheumatoid arthritis
Objective This observational cohort study investigated the impact of biological (b) disease-modifying antirheumatic drugs (DMARDs) on the outcomes of serious infections (SIs) in patients with ...
BMJ6d
OP0020 Identification of Multiple Sjögren’s Syndrome Susceptibility Loci
Background Sjögren’s syndrome (SS) is a common, clinically heterogeneous autoimmune disease characterized by exocrine gland dysfunction that involves both innate and adaptive immune responses. A ...
BMJ9d
Efficacy and safety of risankizumab for active psoriatic arthritis: 24-week results from the randomised, double-blind, phase 3 KEEPsAKE 1 trial
7 CIRI/Rheumatology & Fraunhofer Institute for Translational Medicine and Pharmacology (ITMP), Fraunhofer Cluster of Excellence for Immune-Mediated Disease (CIMD), Goethe University, Frankfurt, ...
BMJ10d
Settings and artefacts relevant in colour/power Doppler ultrasound in rheumatology
The Parker Institute, Frederiksberg Hospital, Copenhagen University Hospital, The Capital Region of Denmark, DK-2000 Copenhagen F, Denmark Søren Torp-Pedersen, The Parker Institute, Frederiksberg ...
BMJ11d
Rituximab for IgG4-related disease: a prospective, open-label trial
Objectives To evaluate the efficacy of rituximab (RTX) in IgG4-related disease (IgG4-RD) in an open-label pilot trial. Methods We treated 30 IgG4-RD patients with two doses of RTX (1000 mg each). The ...
BMJ12d
Smoking increases peptidylarginine deiminase 2 enzyme expression in human lungs and increases citrullination in BAL cells
Department of Medicine, Division of Respiratory Medicine, Karolinska University Hospital, Solna, Karolinska Institutet, Stockholm, Sweden Dr A I Catrina, Rheumatology ...
BMJ13d
Non-steroidal anti-inflammatory drugs and risk of cardiovascular disease in patients with rheumatoid arthritis: a nationwide cohort study
1 Department of Cardiology, Copenhagen University Hospital Gentofte, Hellerup, Denmark 2 Department of Rheumatology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark 3 Department of ...
BMJ13d
Global, regional and national burden of osteoarthritis 1990-2017: a systematic analysis of the Global Burden of Disease Study 2017
Objectives To report the level and trends of prevalence, incidence and years lived with disability (YLDs) for osteoarthritis (OA) in 195 countries and territories from 1990 to 2017 by age, sex and ...
BMJ14d
Update of EULAR recommendations for the treatment of systemic sclerosis
The aim was to update the 2009 European League against Rheumatism (EULAR) recommendations for the treatment of systemic sclerosis (SSc), with attention to new therapeutic questions. Update of the ...
BMJ15d
L-arginine metabolism inhibits arthritis and inflammatory bone loss
Objectives To investigate the effect of the L-arginine metabolism on arthritis and inflammation-mediated bone loss. Methods L-arginine was applied to three arthritis models (collagen-induced arthritis ...