Introduction With approximately 50% of the drugs being prescribed off-label, the pediatric population is in need for an innovative approach to establish harmonized, best evidence-based dosing ...

Fibre is an essential nutrient in the human diet that is crucial for human health. It provides a range of functional benefits, including stool bulking, and physiological benefits through fermentation ...

A review of the history of confidential enquiries The Confidential Enquiry into Maternal and Child Health (CEMACH) was established in April 2003. It replaces CESDI (the Confidential Enquiry into ...

Methods All children (under 16 year) who had a DMSA scan following UTI in 2007 (Jan-July) prior to the introduction of the NICE guidelines were identified, and compared with those undergoing DMSA ...

The most recent in a series of dangerous social media trends has seen children ingesting large quantities of nutmeg in an attempt to gain a natural ‘high’. Over the past 20 years, there has been a ...

Objective To study the clinical and epidemiological characteristics of complex regional pain syndrome (CRPS) in children. Patients and methods All children and adolescents under 16 years of age with a ...

BACKGROUND Antenatal screening for cystic fibrosis has been endorsed by the US National Institutes of Health. Edinburgh is the only city in the UK with an established routine antenatal screening ...

Background Increasing numbers of children and adolescents experiencing gender dysphoria/incongruence are being referred to specialist gender services. There are various guidelines outlining approaches ...

Objective To investigate, among children with inflammatory bowel disease (IBD) and elevated liver enzymes, what threshold of gamma-glutamyltransferase (GGT) best distinguishes those with and without ...

Objective To establish a birth rate for catecholaminergic polymorphic ventricular tachycardia (CPVT) diagnosed in childhood and observe trends in presentation and management. Design Retrospective ...

A series of systematic reviews commissioned by the Cass Review and published in Archives of Disease in Childhood.

Parents’ ability to provide consent: the zone of parental responsibility ...