Minimally invasive surgery can fix heart valve issue

It’s a serious heart defect that can cause blood to flow into the wrong part of the heart chamber, and up until recently, it ...
Zacks Investment Research on MSN

EW wins FDA approval for SAPIEN M3 as first transseptal TMVR therapy

Edwards Lifesciences EW announced that the FDA approved its SAPIEN M3 transcatheter mitral valve replacement system, making ...
American College of Cardiology

Aortic Valve Calcification and Aortic Stenosis, Microvascular Resistance Reserve After PCI, Microvascular Injury Patterns

In this week’s View, Dr. Eagle looks at the diagnostic value of aortic valve calcification levels in the assessment of low-gradient aortic stenosis. He then examines the prognostic value of ...
ahajournals.org

Abstract 4368252: A Novel Role for ANPEP in Osteogenic Signaling and Aortic Valve Calcification

Introduction: Calcific aortic valve disease (CAVD) is one of the most common valvular diseases, predominantly characterized by progressive calcification of the aortic valve. Although minimally ...
Frontiers

Oxidative low-density lipoprotein and shear induced calcification within a calcific aortic valve disease-on-a-chip platform

Background: Early-stage calcific aortic valve disease (CAVD) has been characterized by the infiltration of immune cells, reorganization of the extracellular matrix, and the deposition and oxidation of ...
Frontiers

Gastrodin mitigates aortic valve calcification by inhibiting glycolysis and histone lactylation through interfering with valve interstitial cells

VICs were cultured in high-glucose Dulbecco’s Modified Eagle Medium (DMEM) supplemented with 10% fetal bovine serum (FBS) and 1% penicillin-streptomycin (Pen/Strep). Osteogenic medium (OM, Stem Cell ...
IEEE

Deep Learning-Driven Automated Aortic Valve Calcification Assessment in CT Calcium Score Screening Images

Abstract: Aortic valve stenosis (AVS) is the most common valvular disease and the third most common cardiovascular disease, with a growing impact in the aging population. AVS culminates in heart ...
BMJ

Outcomes of transcatheter aortic valve replacement in bicuspid versus tricuspid aortic stenosis with severe calcification

Background The comparative outcomes of transcatheter aortic valve replacement (TAVR) in bicuspid versus tricuspid aortic stenosis (AS) with severe calcification remain unclear. This study aimed to ...
TCTMD

Solid Durability Seen With Surgical Resilia Tissue Aortic Valve

Surgical bioprosthetic aortic valves made with bioengineered Resilia tissue (Edwards Lifesciences) appear to suffer less structural deterioration over 8 years compared with similar devices made of ...
American College of Cardiology

Extracoronary Calcification Increases Risk of Incident HF, HFpEF

Among a cohort of multiethnic participants without baseline cardiovascular disease, the presence of extracoronary calcification (ECC) at baseline was independently associated with an increased risk ...
today.ucsd

How a Y Chromosome Gene May Shape the Course of Heart Valve Disease

Rayyan Gorashi (left) and Brian Aguado (right) celebrate the publication of their study in Science Advances that uncovers new mechanisms into how the early stages of aortic valve stenosis unfold ...