Jacqui’s heart transplant gives her a new lease on life, but when the Covid pandemic arrives, the boundaries of an immunocompromised life in a hostile political climate become painfully clear.

A 60-year-old man with hypertension and bipolar disorder was incidentally found to have small cysts on his kidneys during MRI of the abdomen.

Intravenous thrombolysis remains a standard treatment for acute ischemic stroke within 4.5 hours after onset. Vascular reocclusion may occur after intravenous thrombolysis and may be preventable ...

Musunuru and colleagues1 describe in the Journal an innovative approach in which gene editing is applied in the treatment of a very rare disease, the severe urea-cycle disorder carbamoyl-phosphate ...

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Explore a collection of articles and other resources on the Coronavirus (Covid-19) outbreak, including clinical reports, management guidelines, and commentary.

Hereditary angioedema is a rare genetic disease that may include recurrent attacks of cutaneous angioedema, severe abdominal pain, and airway compromise. Prophylaxis and treatment include C1 inhibi ...

On January 2, 2022, Israel began administering a fourth dose of BNT162b2 vaccine to persons 60 years of age or older. Data are needed regarding the effect of the fourth dose on rates of confirmed s ...

A patient with a 33-year history of HIV-1 infection who underwent stem-cell transplantation for the treatment of acute myelogenous leukemia remained HIV-1 free nearly 5 years later.

Acute kidney injury is common, with a major effect on morbidity and health care utilization. Soluble urokinase plasminogen activator receptor (suPAR) is a signaling glycoprotein thought to be invol ...

Acute kidney injury is associated with many short- and long-term adverse events. This review considers the cardiovascular consequences and strategies that can be used during acute kidney injury ...

The authors review the pathophysiology, revised diagnostic definitions, and management of acute kidney injury, a common condition in patients with cirrhosis.