In a recent study posted to the bioRxiv* preprint server, researchers assessed the roles of the interferon (IFN) regulatory factors (IRFs): IRF1, IRF3, and IRF7 in infections by human coronaviruses ...

Interferons are proteins that are part of your natural defenses. They tell your immune system that germs or cancer cells are in your body. And they trigger killer immune cells to fight those invaders.

In a recent study published in Science Immunology, researchers investigated whether individuals with breakthrough infections of severe coronavirus disease 2019 (COVID-19) pneumonia demonstrated normal ...

A recent study in the journal PNAS from the lab of Julie Overbaugh reveals a previously unknown antiviral function of a gene involved in the immune defense against Zika virus that has implications for ...

Inhaled interferon-gamma may be an effective treatment for idiopathic pulmonary fibrosis (IPF), a chronic and progressive form of lung disease caused by excessive formation of fibrotic, or scar tissue ...

Over the past decade, the pharmaceutical pipeline has become packed with small molecules that treat the hepatitis C virus (HCV). Hopes are high that the current standard of care—a combination of ...

Despite potential benefits, the therapy remains in limited use for myeloproliferative neoplasms (MPNs). Pegylated interferons are a meaningful therapeutic option for the treatment of ...

A major study validates the GOLDEN model as an accurate tool for predicting HBsAg loss in interferon-treated chronic ...