"We're doing what we need to do," Israeli PM Benjamin Netanyahu tells Jon Karl about the possibility of taking out Iran's Supreme Leader while discussing the conflict with Iran.

Khamenei has condemned the attacks and promised to retaliate, saying Israel had "sealed for itself a bitter and painful destiny."

Netanyahu reveals Iran attempted to assassinate both him and Trump, discusses Israel's strikes against Iran's nuclear program, and explains the "imminent threat."

As the attacks escalate, with fatalities and injuries reported on both sides, Israel issued the stark warning to Iran.

As tensions rise after Israeli airstrikes on Iran's nuclear sites, Prime Minister Netanyahu accused Iran of plotting against the U.S. president.

EXCLUSIVE: Israeli Prime Minister Benjamin Netanyahu doesn't rule out eliminating Iran's supreme leader in an ABC News interview.

Donald Trump declared that, “for the first time in a thousand years, the world will look at this region not as a place of turmoil and strife, and war and death, but as a land of opportunity and hope.”

Iran called on U.S. President Donald Trump on Monday to force Israel to cease fire as the only way to end the four-day-old aerial war, while Israeli Prime Minister Benjamin Netanyahu said his country was on the "path to victory".