G-protein-coupled receptors (GPCRs) are one of the largest families of cell surface proteins in the human body that recognize ...

Explore AI in drug discovery and its journey from promise to proof in 2025 with significant achievements and challenges faced.

Antimicrobial resistance (AMR) is diminishing the effectiveness of existing antibiotics and intensifying the need for discovery pipelines that are both ...

In recent years, target-based drug discovery has undergone a renaissance thanks to polypharmacology. In contrast to the conventional lock-and-key or one target-one drug model of drug design, ...

AI has fundamentally altered the feasibility of natural product discovery from fungal endophytes. Advances in genome sequencing, metabolomics, and systems biology have generated vast datasets, but ...

Smart multi-target drugs are reshaping modern therapeutics by addressing the complex, interconnected pathways that drive diseases like Alzheimer’s, cancer, and major depressive disorder. Advances in ...

Artificial intelligence (AI) deep learning is rapidly transforming the biotechnology and pharmaceutical industries. New AI models based on ChatGPT-like algorithms are emerging in many industry ...

Discover how researchers are overcoming the limitations of the undruggable target in drug discovery using novel approaches ...

Developing high-quality, safe, and effective drugs is a complex process that requires varied scientific skills and stringent regulatory assessments. Drug development is a process that spans many years ...