Researchers have developed a cost-effective conversion that turns a standard epifluorescence microscope into a focus-stabilized TIRF platform achieving sub-10-nanometer DNA-PAINT and (d)STORM imaging.

Stick a soda straw into a glass of water, and from the side, the straw will appear to bend at the interface between air and water. That effect is caused by the different refractive indexes of the air ...

In recent years, Total Internal Reflection Fluorescence (TIRF) microscopy has become an important method for studying molecular interactions near the cell surface. To accommodate the trend of the ...

TIRF microscopy uses the principle of total internal reflection to selectively activate fluorophores near the slide-sample interface while ignoring more deeply embedded ones. That makes the technique ...

Scientists at the National Institute of Biomedical Imaging and Bioengineering (NIBIB) have combined two different microscope technologies to create sharper images of rapidly moving processes inside a ...

The goal of the Microscopic Imaging Core is to provide the equipment, support, and training needed by faculty and students to perform advanced cell biology, biochemistry, and histopathology studies ...