Lasso peptides (LaPs), characterized by their entangled slipknot-like structures, are a large class of ribosomally synthesized and post-translationally modified peptides (RiPPs), with examples ...

The identification of therapeutically interesting compounds from the estimated 10 60 potential drug-like chemicals remains a critical challenge in drug discovery 1. High-throughput screening is widely ...

A University of Missouri researcher has created a computer program that can unravel the mysteries of how proteins work together—giving scientists valuable insights to better prevent, diagnose and ...

A study from Cornell researchers could enable a quantum leap forward in identifying and deciphering cancer-driving genetic mutations, the first step in developing effective therapeutics. Cells become ...

As Biohub unveiled the next-generation ESM, AI tools designed to model protein biology, Northwestern University scientist Shana Kelley said the innovations will help write “the book of life.” A ...