Rheumatoid arthritis is a chronic autoimmune disease that affects millions of people worldwide. This disease prompts the immune system to mistakenly attack body tissues, particularly joints, leading ...

Scientists at the University of Science and Technology of China have identified a signaling chain that starts with gut ...

Cancer-fighting T cells do not simply "run out of energy." They are molecularly reprogrammed. For years, mitochondrial ...

Colorectal cancer remains one of the leading causes of cancer-related mortality worldwide, largely due to metastasis and ...

T cell activation—the process by which these key immune defenders recognize threats and mobilize against them—depends on exquisitely timed molecular signals. Now researchers have captured one of the ...

Researchers have uncovered a surprising molecular chain reaction in the brain that may play a role in some forms of autism. The study suggests that nitric oxide, a tiny signaling molecule normally ...

A tissue section from a mouse model of lung metastasis showing cancer cells (green) that have attracted and activated fibroblasts (red) to support the growth of a metastatic tumor. Image: Massagué Lab ...

Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...

Researchers show that pharmacological activation of hypoxia signaling improves metabolism, limits fat accumulation, and ...

Researchers analyze 2.2 million genomes to show that addiction risk is primarily driven by broad genes affecting brain wiring and impulse control, not drug-specific traits.