Diffuse intrinsic pontine gliomas (DIPGs), with a median survival of 9 months, represent the biggest therapeutic challenge in pediatric neuro-oncology. Despite many clinical trials, no major ...

A 32-year-old man presents with the chief complaint of a "brain lesion." He is a fitness buff and lifts weights at a gym at least 4 days a week. Approximately 1 month ago, he developed a generalized ...

The first step in the evaluation of a patient with neurologic symptoms is the neuroanatomic localization of the lesion. It would be interesting to know further detail about the presenting symptoms: ...

A 29 year-old woman presented with loss of coordination affecting the right arm and leg. Multiple Sclerosis (MS): (Left and Middle) Flair axial MRIs; (Right) T1-weighted with gadolinium (GAD) axial ...

A 32-year-old female with relapsing remitting multiple sclerosis (MS) diagnosed 6 years previously presents at hospital in November 2015. She reports difficulty walking, which she says has worsened ...

A 57 year-old woman with diabetes developed a right sided hemiparesis. There was no aphasia. Pontine Infarction: (Left) T2 weighted-axial MRI; (Right) Diffusion-weighted MRI. Note the bright signal in ...

Show More From the Necker Enfants Malades Hospital, Université Paris Descartes, Sorbonne Paris Cité, France; Gustave Roussy Cancer Institute, Universite Paris Sud, Villejuif, France. Diffuse intrinsic ...