Charles Burger, MD: Pulmonary hypertension really refers to a state where the right heart is generating high pressures to circulate the blood through the lung. Pulmonary arterial hypertension is a ...
A recent study published in Frontiers in Immunology discussed how injury and abnormal repair of the airway epithelium drive chronic obstructive pulmonary disease (COPD) and asthma. Study: Mechanisms ...
—Investigators from the U.S. and U.K have identified neutrophil elastase (NE) and its inhibitor elafin as possible biomarkers in the pathogenesis of pulmonary arterial hypertension (PAH). “An ...
Erdosteine is a multimechanism, mucolytic agent that decreases the sputum viscoelastic properties and bacterial adhesion to the cell membrane, endowed with bronchial anti-inflammatory activity and a ...
Alterations in metabolism of lipids, amino acids, glucose, nucleotides, and pulmonary and gut microbiome play a crucial role in COPD development. These metabolites have great potential as early ...
Further investigation on the pathogenesis and treatment of patients with schistosome-associated pulmonary arterial hypertension (Sch-PAH) may lead to improved symptoms and higher rates of survival. A ...
"Taken together the interplay of sex-specific gene regulation and its impact on ECM-related genes, influenced by factors such as genetics, epigenetics, environmental exposures, steroid hormones, aging ...
Chronic obstructive pulmonary disease (COPD) is among the most leading causes of death around the world and there are insufficient treatment options that prevent exacerbations or alter the progression ...
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