Rather than completely blocking all downstream signals, the peptide developed in this study focuses on inhibiting the activation of p38-MAPK. This is enough to downregulate the development of mature ...
Osteoporosis is a common skeletal disorder characterized by excessive bone loss, leading to increased fragility and an increased risk of fractures. Osteoclasts, the bone-resorbing cells, are widely ...
Osteoporosis is a common skeletal disorder characterized by excessive bone loss, leading to increased fragility and an increased risk of fractures. Osteoclasts, the bone-resorbing cells, are widely ...
Rheumatoid arthritis (RA) is characterized by joint inflammation and progressive joint damage — a major cause of the progressive disability characteristic of RA patients. However, despite the ...
A transformative study has uncovered the pivotal role of the protein Naked cuticle homolog 2 (NKD2) in regulating the differentiation of bone-forming osteoblasts and bone-resorbing osteoclasts. This ...
Osteocytes, the most abundant cells in bone tissue, have long been underestimated in their functional capacity. Traditionally viewed as passive entities, recent research has illuminated their pivotal ...
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