Chemists discover how key contrast agent works, paving a way to create new markers needed for correlative microscopy that can image the structure and signaling of cells at the same time. Two labs at ...

Liquid cell electron microscopy (LC-EM) has emerged as a transformative tool for observing nanoparticles in their native, fluid environment with nanometre spatial resolution and millisecond temporal ...

Nearly 100 years ago, a seemingly simple discovery revolutionized the microscope. The introduction of phase-contrast, which garnered a Nobel Prize in 1953, brought into clear view structures inside ...

Basic techniques for observing the microscopic structure of the human body —Histology is the study of understanding the human ...

There are many ways to observe mitochondria now, aren't there? But in reality, every technique inevitably has some trade-offs ...

Stanford researchers have combined two microscopy techniques to create a one-of-a-kind instrument that can show cell structures interacting in real time at an unprecedented 120-nanometer ...

It takes just a few milliseconds: A vesicle, only a few nanometers in size and filled with neurotransmitters, approaches a cell membrane, fuses with it, and releases its chemical messengers into the ...

Scientists have developed a new imaging technique that uses a novel contrast mechanism in bioimaging to merge the strengths of two powerful microscopy methods, allowing researchers to see both the ...

Scientists have developed a new imaging technique that uses a novel contrast mechanism in bioimaging to merge the strengths of two powerful microscopy methods, allowing researchers to see both the ...

Electron microscopy is a powerful technique that provides high-resolution images by focusing a beam of electrons to reveal fine structural details in biological and material specimens. 2 Because ...

Using a tiny, spherical glass lens sandwiched between two brass plates, the seventeenth century Dutch microscopist Antonie van Leeuwenhoek was the first to officially describe red blood cells and ...

Bridging physics and materials engineering, Manling Sui pushes the boundaries of electron microscopy while advocating for ...