Several studies showed that supplementation of oviductal extracellular vesicles (EVs) enhanced the development and quality of the early embryos cultured in vitro. However, our previous study found ...
Current single-cell atlases of mouse embryos are limited in temporal resolution and cellular or sequencing depth coverage. Here we report the mouse developmental Cell and Lineage Atlas (mdCLA), which ...
A discovery upends decades of assumptions regarding DNA replication. The study show that DNA replication in early embryos is different from what past research has taught, and includes a period of ...
A recent study delves into the pivotal role of Setd2, a histone methyltransferase enzyme, in embryonic development within mice. Setd2 is instrumental in the trimethylation of histone H3 lysine 36 ...
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