A graphic of a purple and magenta Cas9 protein, which is a somewhat round, but uneven, ball, bound to a yellow and orange ...

CDCA7, whose mutations alter DNA methylation pattern and cause immunodeficiency, is a novel sensor for a special class of methylated DNA. DNA methylation is a process in which a methyl group is ...

Cancer cells excel at evading detection, but subtle chemical differences set them apart from healthy cells. Now, a team of ...

The epigenetic modification, DNA methylation, is characterized by 5-methylcytosine (5-mC) and found in specific genomic locations, most notably regulatory regions such as promoters and enhancers.

The first complete DNA methylation atlas of 39 human cell types reveals which genes can talk or are silenced, depending on whether their sequence is linked to methyl group epigenetic modification that ...

From the unveiling of a cloud-based computational platform for metabolomics data analysis, to demonstrating the efficacy and safety of therapeutic antibodies using an innovative mouse model, here are ...

Women With Synchronous Primary Cancers of the Endometrium and Ovary: Do They Have Lynch Syndrome? Currently, no validated blood-based assays accurately predict treatment response or outcome in ...

Most gene-editing tools are blind to context. Point them at a DNA sequence and they cut, whether that sequence sits inside a ...

Cancer cells have ways to hide from the immune system, but there are some unique features on these dangerous cells that ...

Most gene-editing tools cut DNA wherever they’re pointed, with no way to tell a tumor cell from a healthy one. A study ...