Recent evidence highlights the complex interplay between the central nervous system and hepatic drug-metabolising enzymes. In particular, the regulation of liver cytochrome P450 (CYP) enzymes by ...

This is a preview. Log in through your library . Abstract It has been shown in previous studies that liver HEP-G2 cells (human hepatocellular carcinoma) lose their ability to express active alcohol ...

Elderly Patients Have Become the Leading Drug Consumers: It's High Time to Properly Evaluate New Drugs Within the Real Targeted Population ...

Statin Available to Treat Patients with Primary Hyperlipidemia or Mixed Dyslipidemia MONTGOMERY, Ala. and INDIANAPOLIS, June 21, 2010 /PRNewswire via COMTEX News Network/ -- Kowa Pharmaceuticals ...

SAN DIEGO--(BUSINESS WIRE)--Metabasis Therapeutics, Inc. (Nasdaq: MBRX), announced today the publication of four articles on MB07811, its product candidate for treating hyperlipidemia. The articles ...

Inspired by what human liver enzymes can do, chemists have developed a new set of copper-catalyzed organic synthesis reactions for building and modifying pharmaceuticals and other molecules. The new ...