A new study from the laboratory of Hiroki Ueda at the RIKEN Quantitative Biology Center investigates circadian timekeeping with a novel approach to creating genetic knock-out rescue mice. Published in ...

The research team discovered that Arvcf knockout significantly reduces the neuronal abundance within the VTA and weakens ...

More than 70 genes have been linked to autism spectrum disorder (ASD), a developmental condition in which differences in the brain lead to a host of altered behaviors, including issues with language, ...

Mouse models for hemophilia A are commonly generated by factor VIII (FVIII) knockout, however, these mice rapidly develop anti-FVIII antibodies during repetitive FVIII administration. To overcome this ...

Explore the SHANK3 knockout model to enhance research in Phelan-McDermid syndrome and neurodevelopmental disorders.

There are over 70 genes that have been associated with autism spectrum disorder, but some of them are only the cause of ASD in a handful of patients. While each those genes can provide some insight ...

Metabolic dysfunction-associated steatotic liver disease (MASLD), is the most common form of chronic liver disease worldwide. This study aimed to explore the role of TM6SF2 in high-fat diet ...