Spinal cord injuries cause permanent paralysis in part because inflammation, cell death, and glial scarring block nerve regeneration, and there has been no reliable human tissue model to test ...

The spinal cord plays a central role in integrating sensory and motor information to regulate movement. This is achieved by the coordinated function of motor neurons (MNs) and other neuronal and glial ...

Damage to the spinal cord can lead to irreversible paralysis and loss of sensory function, but translation of preclinical therapies remains elusive. We recently showed that bioactive supramolecular ...

Northwestern University (IL, USA) scientists have developed the most advanced organoid model for human spinal cord injury to date. In a new study, the research team used lab-grown human spinal cord ...

Fluorescent micrographs showing increased neurite outgrowth from a human spinal cord organoid treated with fast-moving “dancing molecules” (left) compared to one treated with slow-moving molecules ...