The discovery of the Tetrahymena group I intron’s self-splicing defined RNAs as capable catalysts. Now, cryogenic electron microscopy structures of this ribozyme have revealed large conformational ...
A team led by Prof. Zhang Kaiming from the University of Science and Technology (USTC) solved six conformations in the second-step self-splicing of Tetrahymena ribozyme using cryogenic electron ...
Researchers confirm that the established pre-mRNA splicing mechanism that appears in textbooks cannot work in a subset of human short introns: A novel SAP30BP–RBM17 complex-dependent splicing has been ...
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