Cells have evolved careful checks to ensure DNA is copied only once, but how they switch on replication at the right moment ...

If you are anything like us, whenever you plan a journey, you spend a remarkable amount of time thinking about the start and ...

The DNA packed inside every human cell contains instructions for life, written in billions of letters of genetic code. Every time a cell divides, the complete code, divided among 46 chromosomes, must ...

The emergence, organization, and persistence of cellular life are the result of the functional integration of metabolic and genetic networks. Here, we engineer phospholipid vesicles that can operate ...

Replication timing (RT), the temporal order in which genomic regions replicate, is considered a functional feature of multiple cellular processes and chromatin organization. Two approaches to measure ...

A new study has uncovered a hidden step that helps the deadliest malaria parasite survive and multiply inside the human body. Researchers studying Plasmodium falciparum found that the parasite relies ...

In turn, this slowed new DNA synthesis at replication forks, structures in which double strands of DNA separate to begin the copying process. The cells' attempt to restart the stalled replication fork ...