Researchers at Umeå University have conducted a unique three-dimensional mapping of an entire human pancreas. The study shows ...

The gut–islets axis connects nutrient sensing in the intestine with insulin secretion from the pancreas and plays an essential role in glucose regulation. GLP-1 released by intestinal L cells can ...

Researchers analyzed pancreatic islets from 299 donors and found that differences in alpha, beta, and delta cell composition ...

How do living cells respond to physical forces, including those relayed from the complex cellular and extracellular microenvironment within a tissue? We know that these forces affect nearly every ...

We report on a 43-year-old woman with a 25-year history of type 1 diabetes. Her weight was 53.4 kg (117.7 lb), and her body-mass index (the weight in kilograms divided by the square of the height in ...

PSC-derived cells can reverse type 1 diabetes in mice and may overcome some of the hurdles faced by existing stem cell ...

Researchers at Umeå University have conducted a unique three-dimensional mapping of an entire human pancreas. The study shows ...

Immunofluorescence image of the pancreatic islets of a 50-year-old-female without diabetes. This individual had 54% beta cells (GREEN), 9% delta cells (WHITE) and 37% alpha cells (RED). Diabetes is ...

Professor Deng Hongkui's team from the Peking University School of Life Sciences has made the first successful differentiation of human pluripotent stem cells into fully endocrine-subtype-complete ...

The pancreas is an abdominal organ that produces digestive enzymes as well as hormones that regulate blood sugar levels. This hormone-producing function is localized to the islets of Langerhans, which ...