New protocol generated glucose-responsive SC-islets from eight hPSC lines tested, demonstrating potential for autologous applications.

Researchers from the Organoid group (previously Clevers group) at the Hubrecht Institute have developed a new organoid that mimics the human fetal pancreas, offering a clearer view of its early ...

Organoids—tiny, lab-grown 3D clusters of cells—are a useful tool for studying organ development, disease, and drug responses. These miniature organs-in-a-dish are powerful, but they’re not perfect: ...

Professor Deng Hongkui's team from the Peking University School of Life Sciences has made the first successful differentiation of human pluripotent stem cells into fully endocrine-subtype-complete ...

Our glycaemic balance is based on the ability of the pancreatic beta cells to detect glucose and secrete insulin to maintain our blood sugar levels. If these cells malfunction, the balance is broken, ...

A recent study published in Cell Metabolism by researchers at the Hebrew University-Hadassah Medical School, Bar-Ilan University and Vanderbilt University has developed a new paradigm for early stages ...

Researchers have developed a new organoid that mimics the human fetal pancreas, offering a clearer view of its early development. The researchers were able to recreate a complete structure that ...

Type 1 diabetes (T1D) is an autoimmune disorder characterized by the specific destruction of insulin-producing pancreatic β-cells. While islet transplantation has demonstrated promise, its widespread ...

In recent years, nanoplastic and microplastic particles (NMPs) have emerged as substantial threats to human health, particularly as endocrine disruptors. The endocrine system is especially vulnerable ...

Peking University, August 29, 2025: Professor Deng Hongkui’s team from the Peking University School of Life Sciences recently made the first successful differentiation of human pluripotent stem cells ...