After acute injury to the brain, neurons at the damage epicentre depolarize, and this depression of activity spreads outward in waves through the cortex. A recently published study sheds light on how ...
Membrane depolarization activates voltage-dependent Ca²⁺ channels (VDCCs) inducing Ca²⁺ release via ryanodine receptors (RyRs), which is obligatory for skeletal and cardiac muscle contraction and ...