Ruggiano and Ramadan 4 provide an overview of the mechanisms dedicated to removing replication obstacles, such as proteins covalently or tightly bound to DNA. Their work discusses how molecular ...
Hypoxia is common in tumors and is associated with cancer progression and drug resistance, driven, at least in part, by genetic instability. Little is known on how hypoxia affects Translesion DNA ...
Researchers from the University of Birmingham have uncovered answers that provide the detail to explain two specific DNA repair processes that have long been in question. The publication of two papers ...
The Polymerase Chain Reaction (PCR) is a technique for the amplification of DNA in vitro (this describes experiments with cells outside their normal environment). PCR amplifies DNA using complementary ...