This double-blind trial enrolled adults with HIV-associated cryptococcal meningitis in Vietnam, Thailand, Indonesia, Laos, Uganda, and Malawi. All patients received combination antifungal therapy of ...

Dar es Salaam / Lilongwe / Geneva — 15 April 2025 — A new, easier-to-administer and patient-friendly sustained-release formulation of flucytosine, a medicine used to treat cryptococcal meningitis, has ...

C. neoformans is a fungal pathogen that causes meningitis, which causes approximately 180,000 deaths annually worldwide. Currently, AmB is the only fungicidal drug available to treat fungal meningitis ...

SSUCv3H4sIAAAAAAAEAIVSy27DIBC8V+o/WJxj1WDHxf2CXvoFUQ8YNjaKYyIMqarI/971g5SmUnJjZ2eH2cfl+SlJSC0GLclbcpkijHXX ...

There is hope in the fight against cryptococcal meningitis, the second leading cause of death in patients with advanced HIV (previously called AIDS), as scientists work around the clock to release new ...

In a recent study published in Nature Microbiology, researchers examined metabolite-drug-fungal interactions in the fungal meningitis pathogen Cryptococcus neoformans. Antibiotic resistance refers to ...

MINNEAPOLIS/ST. PAUL (08/22/2023) —A team of University of Minnesota Medical School researchers successfully tested a new antifungal therapy to treat fungal meningitis. The trial results were ...

The encapsulated fungus Cryptococcus neoformans is the most common cause of fungal meningitis, with the highest rate of cryptococcosis found in AIDS patients. Despite antifungal treatment, ...

The Nature Index 2025 Research Leaders — previously known as Annual Tables — reveal the leading institutions and countries/territories in the natural and health sciences, according to their output in ...

Cryptococcal meningitis is a major complication of HIV infection. In this phase 3, randomized, controlled trial in sub-Saharan Africa, a single dose of liposomal amphotericin B induction therapy ...

A map of deadly infectious diseases known to attack the central nervous system (CNS) of people who are already suffering with HIV has unearthed diagnosis "blank spots" in Africa, according to research ...