Genes encode proteins and proteins dictate cell function. Therefore, the thousands of genes expressed in a particular cell determine what that cell can do. Moreover, each step in the flow of ...

It could be simply to control gene expression." The study, "Global impact of unproductive splicing on human gene expression levels and traits," was supported by funding from the National Institutes of ...

Our circadian clocks play a crucial role in our health and well-being, keeping our 24-hour biological cycles in sync with ...

Turning genes on and off is like flipping a light switch, controlling whether genes in a cell are active. When a gene is turned on, the production of proteins or other substances is promoted; when ...

Most people recognize Alzheimer's from its devastating symptoms such as memory loss, while new drugs target pathological aspects of disease manifestations, such as plaques of amyloid proteins. Now a ...

A study published today in the journal Cell marks the first reported instance of generative AI designing synthetic molecules that can successfully control gene expression in healthy mammalian cells.

Alternative splicing is a genetic process where different segments of genes are removed, and the remaining pieces are joined together during transcription to messenger RNA (mRNA). This mechanism ...

A figure from the paper illustates a key finding of "compromised compartmentalization": chromatin that was locking genes down in health became more open in Alzheimer's, while chromatin that was open ...