The initiation of chromosome replication is exquisitely regulated in both time and location. It has been estimated that there are 200-400 autosomal replication sequence elements (ARSs) in the yeast ...

Vibrio cholerae presents a unique model of bacterial genome organisation through its bipartite genome, comprising two distinct chromosomes that replicate in a carefully orchestrated manner. The ...

The DNA packed inside every human cell contains instructions for life, written in billions of letters of genetic code. Every time a cell divides, the complete code, divided among 46 chromosomes, must ...

New findings suggest the end-replication problem, an old standby of biology textbooks, is twice as intricate as once thought. Half a century ago, scientists Jim Watson and Alexey Olovnikov ...

E. coli divides faster than it can replicate its genome, while simultaneously expressing its genes. Scientists recently revealed the intricate molecular coordination that makes this possible. “It’s as ...

During the replication of the bacterial chromosome, genes close to the replication start point (red) exist in multiple copies, while genes close to the endpoint do not (blue). At faster growth, this ...

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published in Nature. Chromosomes are thread-like structures that carry a cell's ...

Chromosomes are tightly coiled structures in each of your cells that contain DNA, the code for all life. DNA is organized in segments on chromosomes called genes. Humans typically have 46 chromosomes ...

Half a century ago, scientists Jim Watson and Alexey Olovnikov independently realized that there was a problem with how our DNA gets copied. A quirk of linear DNA replication dictated that telomeres ...