A research group is the first in the world to succeed in constructing artificial cell nuclei by injecting purified DNA solution instead of sperm into living mouse eggs. Their findings are published in ...

Researchers at the University of Jyväskylä (Finland), in cooperation with national and international research groups, have ...

A recent international research project has used advanced microscopy techniques and computational modeling to discover why virus infection changes the nuclear structures and biomechanical forces ...

Gene therapy holds the promise of preventing and curing disease by manipulating gene expression within a patient's cells. However, to be effective, the new gene must make it into a cell's nucleus. The ...

In tissue biopsies, cancer cells are frequently observed to have nuclei (the cell's genetic information storage) that are larger than normal. Until now, this was considered a sign that the cancer was ...

Researchers at the Francis Crick Institute have shown that the 'pacemaker' controlling yeast cell division lies inside the nucleus rather than outside it, as previously thought. Having the pacemaker ...

Researchers have used advanced microscopy and computational modeling to show how herpesvirus infection affects host-cell nucleus structure.

Cancer cells are subjected to high mechanical pressure that leads to a rupture of the nuclear envelope when migrating through narrow tissue structures, as in the case of metastasis. DNA would normally ...