The optimal way to manage vancomycin dosing is through AUC-guided dosing. Per consensus guidelines published in 2020, targeting AUC is both optimal and feasible, allowing patient dosing that maximizes ...
Antibiotic optimisation through therapeutic drug monitoring (TDM) is a key strategy in tackling antimicrobial resistance. However, current quantification methods rely on laboratory-based equipment, ...
Industry groups and drugmakers want the US Food and Drug Administration (FDA) to explicitly clarify that Bayesian statistical methods can be used for products beyond those intended for children and ...
New FDA guidance on the use of Bayesian statistics signals a broader shift in accommodating more flexible clinical trial ...
JUPITER, Fla.--(BUSINESS WIRE)--DoseMe, a leader in model-informed precision dosing (MIPD), today announced that Senior Care Partners (PACE) has implemented DoseMeRx to modernize vancomycin dosing in ...
Timing of troughs Troughs should be obtained at steady state: approximately prior to the fifth dose IIB Optimal trough concentrations Should be >10 mg/l at a minimum to avoid development of ...
Objective: To systematically evaluate the literature to determine whether vancomycin-induced neutropenia is dose- or duration-related and provide clinicians with feasible treatment alternatives. Data ...
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