Novel generative AI model enables atomic-scale prediction of protein-protein interactions

Proteins are the molecular workhorses of the human body. They perform a vast range of essential functions, from building ...
Nature

Automated model building and protein identification in cryo-EM maps

Interpreting electron cryo-microscopy (cryo-EM) maps with atomic models requires high levels of expertise and labour-intensive manual intervention in three-dimensional computer graphics programs 1,2.
Nature

When cryo-EM modeling meets structure prediction

Accurately interpreting density maps into atomic models is a central yet challenging goal of cryo-EM. Two studies now reveal distinct ways in which protein structure prediction can be incorporated ...