Bacteria use a variety of mechanisms to render antimicrobials ineffective: efflux pumps that remove compounds from the cell, enzymatic degradation of an antimicrobial compound, and modification of a ...

At WIRED Health, British surgeon Ara Darzi said AI is set to transform the diagnosis and treatment of drug-resistant infections. But a lack of incentives means innovation may not reach patients.

A newly discovered mechanism renders antibiotic-resistant bacteria vulnerable by disabling both their individual resistance ...

Scientists have mapped in unprecedented detail the structure of Vibrio bacteria, which can cause life-threatening infections ...

Experimental design and workflow of AMP prediction using in silico tools and 3D HT-HTS. Hirunipin 2 as a selected AMP candidate was evaluated on antibacterial, antibiofilm, antiinflammatory activiry ...

A new analysis shows that infectious bacteria exposed to the antibiotic albicidin rapidly develop up to a 1,000-fold increase in resistance via a gene amplification mechanism. A new analysis shows ...

Sexually transmitted infection (STI) gonorrhea is on the rise as a major public health burden worldwide, with around 87 million new infections a year largely caused by the superbug Neisseria ...

McMaster University researchers have developed SyntheMol-RL, a generative AI model that rapidly designs novel, synthesizable ...

Antibiotic resistance is a major public health problem. Few new molecules are in development, but a new antibiotic called clovibactin brings hope. This drug, isolated from bacteria that haven't ...

Scientists have taken another step forward on their quest to develop a viable drug based on teixobactin -- a new class of potent natural antibiotic capable of killing superbugs. New research provides ...