Mitochondrial dysfunction and endoplasmic reticulum (ER) stress are considered the key determinants of insulin resistance. Impaired mitochondrial function in obese animals was shown to induce the ER ...
Inducible nitric oxide synthase (iNOS) gene transfer is reported to augment erectile responses in rats, although it is also shown to impair vasorelaxation in cerebral arteries. We investigated the ...
A protein long understood to drive inflammation by producing nitric oxide has a second, previously unknown role - it physically binds to another key protein inside cells to directly modulate the ...
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