Medexus Pharmaceuticals Inc. looks set for its U.S. launch of bifunctional alkylating agent treosulfan in the first half of 2025 following a long-awaited FDA approval of the drug, branded Grafapex, ...
For childhood cancer survivors, there are racial and ethnic disparities in epigenetic age acceleration (EAA), which are partially mediated by social determinants of health (SDOH), according to a study ...
The efficacy of many alkylating chemotherapeutic agents is significantly undermined by the cellular repair protein O6-alkylguanine-DNA alkyltransferase (AGT), which removes cytotoxic alkyl groups from ...
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